Dornase Alfa
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00003 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | osteogenesis imperfecta | KG + DL |
| 2 | autosomal recessive nonsyndromic deafness | KG + DL |
| 3 | congenital stationary night blindness autosomal dominant | KG + DL |
| 4 | autosomal dominant nonsyndromic deafness | KG + DL |
| 5 | deafness, autosomal recessive | KG + DL |
| 6 | keratoderma hereditarium mutilans | KG + DL |
| 7 | immunodeficiency-centromeric instability-facial anomalies syndrome | KG + DL |
| 8 | mullerian aplasia and hyperandrogenism | KG + DL |
| 9 | myelodysplasia, immunodeficiency, facial dysmorphism, short stature, and psychomotor delay | KG + DL |
| 10 | GM1 gangliosidosis | KG + DL |
| 11 | bone dysplasia, lethal Holmgren type | KG + DL |
| 12 | predisposition to invasive fungal disease due to CARD9 deficiency | KG + DL |
| 13 | agammaglobulinemia | KG + DL |
| 14 | asymmetric short stature syndrome | KG + DL |
| 15 | action myoclonus-renal failure syndrome | KG + DL |
| 16 | Fanconi anemia complementation group | KG + DL |
| 17 | arthrogryposis, distal, | KG + DL |
| 18 | portal hypertension, noncirrhotic | KG + DL |
| 19 | craniosynostosis-intracranial calcifications syndrome | KG + DL |
| 20 | combined immunodeficiency due to ZAP70 deficiency | KG + DL |
| 21 | ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies | KG + DL |
| 22 | deafness, autosomal dominant | KG + DL |
| 23 | dyskeratosis congenita, autosomal recessive | KG + DL |
| 24 | Brown syndrome | KG + DL |
| 25 | primary microcephaly | KG + DL |
| 26 | brachydactyly | KG + DL |
| 27 | Summitt syndrome | KG + DL |
| 28 | tremor, hereditary essential | KG + DL |
| 29 | familial visceral amyloidosis | KG + DL |
| 30 | trichohepatoenteric syndrome | KG + DL |
| 31 | immunodeficiency, common variable | KG + DL |
| 32 | parastremmatic dwarfism | KG + DL |
| 33 | vitamin B12-responsive methylmalonic acidemia | KG + DL |
| 34 | annular epidermolytic ichthyosis | KG + DL |
| 35 | congenital nystagmus | KG + DL |
| 36 | hyperreflexia (disease) | KG + DL |
| 37 | hidrotic ectodermal dysplasia, Christianson-Fourie type | KG + DL |
| 38 | cherubism | KG + DL |
| 39 | congenital hypotrichosis with juvenile macular dystrophy | KG + DL |
| 40 | acral peeling skin syndrome | KG + DL |
| 41 | mucocutaneous ulceration, chronic | KG + DL |
| 42 | autosomal dominant vibratory urticaria | KG + DL |
| 43 | primary ciliary dyskinesia | KG + DL |
| 44 | spondyloepiphyseal dysplasia with punctate corneal dystrophy | KG + DL |
| 45 | cataract | KG + DL |
| 46 | intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency | KG + DL |
| 47 | familial hyperthyroidism due to mutations in TSH receptor | KG + DL |
| 48 | familial digital arthropathy-brachydactyly | KG + DL |
| 49 | phocomelia-ectrodactyly-deafness-sinus arrhythmia syndrome | KG + DL |
| 50 | xeroderma pigmentosum | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.