Nicotine
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00184 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | nicotine dependence | DL |
| 2 | exercise-induced malignant hyperthermia | KG + DL |
| 3 | migraine with brainstem aura | KG + DL |
| 4 | oppositional defiant disorder (disease) | KG + DL |
| 5 | migraine disorder | KG + DL |
| 6 | blepharospasm | KG + DL |
| 7 | 46,XY disorder of sex development due to testicular steroidogenesis defect | KG + DL |
| 8 | longitudinal vaginal septum | KG + DL |
| 9 | transverse vaginal septum | KG + DL |
| 10 | communication disorder | KG + DL |
| 11 | developmental disorder of mental health | KG + DL |
| 12 | motor nerve neuritis | KG + DL |
| 13 | spasmodic dystonia | KG + DL |
| 14 | tic disorder | KG + DL |
| 15 | primary hereditary glaucoma | KG + DL |
| 16 | stereotypic movement disorder | KG + DL |
| 17 | fetal nicotine spectrum disorder | KG + DL |
| 18 | vestibular neuronitis | KG + DL |
| 19 | brachial plexus neuritis | KG + DL |
| 20 | oromandibular dystonia | KG + DL |
| 21 | focal, segmental or multifocal dystonia | KG + DL |
| 22 | trigeminal autonomic cephalalgia | KG + DL |
| 23 | malignant hyperthermia, susceptibility to | KG + DL |
| 24 | transient tic disorder | KG + DL |
| 25 | headache disorder | KG + DL |
| 26 | female infertility | KG + DL |
| 27 | open-angle glaucoma | KG + DL |
| 28 | dystonia, focal, task-specific | KG + DL |
| 29 | retinal disease | KG + DL |
| 30 | familial periodic paralysis | KG + DL |
| 31 | neuroretinitis | KG + DL |
| 32 | complex neurodevelopmental disorder | KG + DL |
| 33 | X-linked dystonia-parkinsonism | KG + DL |
| 34 | moderate multiminicore disease with hand involvement | KG + DL |
| 35 | focal hand dystonia | KG + DL |
| 36 | neuroendocrine disease | KG + DL |
| 37 | epidural abscess | KG + DL |
| 38 | thyrotoxic periodic paralysis, susceptibility to | KG + DL |
| 39 | central core myopathy | KG + DL |
| 40 | atypical childhood epilepsy with centrotemporal spikes | KG + DL |
| 41 | cryptogenic late-onset epileptic spasms | KG + DL |
| 42 | photosensitive occipital lobe epilepsy | KG + DL |
| 43 | double outlet right ventricle with atrioventricular septal defect, pulmonary stenosis, heterotaxy | KG + DL |
| 44 | congenital multicore myopathy with external ophthalmoplegia | KG + DL |
| 45 | Lennox-Gastaut syndrome | KG + DL |
| 46 | febrile infection-related epilepsy syndrome | KG + DL |
| 47 | cutis verticis gyrata | KG + DL |
| 48 | perioral myoclonia with absences | KG + DL |
| 49 | thyrotoxic periodic paralysis | KG + DL |
| 50 | torsion dystonia with onset in infancy | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.