Hydroxocobalamin
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00200 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 32 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | esophageal varices with bleeding | KG + DL |
| 2 | esophageal varices without bleeding | KG + DL |
| 3 | varicose disease | KG + DL |
| 4 | immune-mediated necrotizing myopathy | KG + DL |
| 5 | antisynthetase syndrome | KG + DL |
| 6 | focal myositis | KG + DL |
| 7 | inflammatory myopathy with abundant macrophages | KG + DL |
| 8 | idiopathic eosinophilic myositis | KG + DL |
| 9 | vitamin deficiency disorder | KG + DL |
| 10 | congenital prothrombin deficiency | KG + DL |
| 11 | biotin metabolic disease | KG + DL |
| 12 | osteogenesis imperfecta-retinopathy-seizures-intellectual disability syndrome | KG + DL |
| 13 | C1 inhibitor deficiency | KG + DL |
| 14 | maternally-inherited mitochondrial myopathy | KG + DL |
| 15 | maternally-inherited mitochondrial dystonia | KG + DL |
| 16 | primary optic atrophy | KG + DL |
| 17 | hypophosphatasia | KG + DL |
| 18 | serpinopathy with toxic serpin polymerization | KG + DL |
| 19 | Steel syndrome | KG + DL |
| 20 | Leber hereditary optic neuropathy | KG + DL |
| 21 | pyridoxine deficiency anemia | KG + DL |
| 22 | dermatomyositis | KG + DL |
| 23 | maternally-inherited Leigh syndrome | KG + DL |
| 24 | leukocyte adhesion deficiency | KG + DL |
| 25 | osteopetrosis | KG + DL |
| 26 | multiple intestinal atresia | KG + DL |
| 27 | selective IgG immunodeficiency | KG + DL |
| 28 | hereditary angioedema with C1Inh deficiency | KG + DL |
| 29 | autosomal recessive Alport syndrome | KG + DL |
| 30 | acrorenal syndrome, autosomal recessive | KG + DL |
| 31 | Pendred syndrome | KG + DL |
| 32 | Immunoerythromyeloid hypoplasia | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.