Aprepitant
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00673 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | nephrogenic syndrome of inappropriate antidiuresis | KG + DL |
| 2 | hypertrichosis (disease) | KG + DL |
| 3 | pulmonary hypertension | KG + DL |
| 4 | leprosy | KG + DL |
| 5 | Ambras type hypertrichosis universalis congenita | KG + DL |
| 6 | malformation syndrome with odontal and/or periodontal component | KG + DL |
| 7 | kyphoscoliotic heart disease | KG + DL |
| 8 | syndrome with a Dandy-Walker malformation as major feature | KG + DL |
| 9 | subarachnoid hemorrhage (disease) | KG + DL |
| 10 | isolated genetic hair shaft abnormality | KG + DL |
| 11 | persistent Mullerian duct syndrome | KG + DL |
| 12 | multiple endocrine neoplasia | KG + DL |
| 13 | nephrogenic diabetes insipidus | KG + DL |
| 14 | pulmonary hypertension, primary, autosomal recessive | KG + DL |
| 15 | obsolete patella aplasia, coxa vara, and tarsal synostosis | KG + DL |
| 16 | chromosome 17q23.1-q23.2 deletion syndrome | KG + DL |
| 17 | familial clubfoot due to 17q23.1q23.2 microduplication | KG + DL |
| 18 | acquired aneurysmal subarachnoid hemorrhage | KG + DL |
| 19 | coxopodopatellar syndrome | KG + DL |
| 20 | hypoalphalipoproteinemia | KG + DL |
| 21 | pneumocystosis | KG + DL |
| 22 | homozygous familial hypercholesterolemia | KG + DL |
| 23 | Cryptococcal meningitis | KG + DL |
| 24 | adult-onset citrullinemia type I | KG + DL |
| 25 | acute neonatal citrullinemia type I | KG + DL |
| 26 | thoracic malformation | KG + DL |
| 27 | hyperargininemia | KG + DL |
| 28 | Jeune syndrome | KG + DL |
| 29 | adult familial nephronophthisis-spastic quadriparesia syndrome | KG + DL |
| 30 | renal-hepatic-pancreatic dysplasia | KG + DL |
| 31 | karyomegalic interstitial nephritis | KG + DL |
| 32 | idiopathic pulmonary arterial hypertension | KG + DL |
| 33 | mitochondrial DNA depletion syndrome, hepatocerebrorenal form | KG + DL |
| 34 | polycystic kidney disease | KG + DL |
| 35 | hereditary renal hypouricemia | KG + DL |
| 36 | benign prostatic hyperplasia (disease) | KG + DL |
| 37 | pulmonary hypertension, primary | KG + DL |
| 38 | common cold | KG + DL |
| 39 | Joubert syndrome with renal defect | KG + DL |
| 40 | cor pulmonale | KG + DL |
| 41 | idiopathic and/or familial pulmonary arterial hypertension | KG + DL |
| 42 | intracranial abscess | KG + DL |
| 43 | familial isolated trichomegaly | KG + DL |
| 44 | urea cycle disorder | KG + DL |
| 45 | polycystic kidney disease 3 with or without polycystic liver disease | KG + DL |
| 46 | migraine disorder | KG + DL |
| 47 | retinitis | KG + DL |
| 48 | gastrointestinal hamartoma | KG + DL |
| 49 | motor nerve neuritis | KG + DL |
| 50 | Senior-Boichis syndrome | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.