Busulfan
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB01008 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | myelodysplastic syndrome | KG + DL |
| 2 | refractory cytopenia of childhood | KG + DL |
| 3 | unclassified myelodysplastic syndrome | KG + DL |
| 4 | partial deletion of the long arm of chromosome 5 | KG + DL |
| 5 | aregenerative anemia | KG + DL |
| 6 | severe congenital hypochromic anemia with ringed sideroblasts | KG + DL |
| 7 | HIV infectious disease | KG + DL |
| 8 | neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | KG + DL |
| 9 | seborrheic keratosis | KG + DL |
| 10 | simian immunodeficiency virus infection | KG + DL |
| 11 | feline acquired immunodeficiency syndrome | KG + DL |
| 12 | rheumatoid arthritis | KG + DL |
| 13 | obsolete familial combined hyperlipidemia | KG + DL |
| 14 | female breast carcinoma | KG + DL |
| 15 | primary cutaneous T-cell lymphoma | KG + DL |
| 16 | vulvar inverted follicular keratosis | KG + DL |
| 17 | multiple sclerosis | KG + DL |
| 18 | granulomatous slack skin disease | KG + DL |
| 19 | seborrheic dermatitis | KG + DL |
| 20 | Crohn’s colitis | KG + DL |
| 21 | sickle cell-beta-thalassemia disease syndrome | KG + DL |
| 22 | sickle cell-hemoglobin c disease syndrome | KG + DL |
| 23 | hereditary persistence of fetal hemoglobin-sickle cell disease syndrome | KG + DL |
| 24 | sickle cell-hemoglobin E disease syndrome | KG + DL |
| 25 | sickle cell-hemoglobin d disease syndrome | KG + DL |
| 26 | autosomal dominant familial hematuria-retinal arteriolar tortuosity-contractures syndrome | KG + DL |
| 27 | brachydactyly-syndactyly syndrome | KG + DL |
| 28 | brain small vessel disease 1 with or without ocular anomalies | KG + DL |
| 29 | rhabdomyosarcoma (disease) | KG + DL |
| 30 | folliculotropic mycosis fungoides | KG + DL |
| 31 | colobomatous microphthalmia-rhizomelic dysplasia syndrome | KG + DL |
| 32 | progressive relapsing multiple sclerosis | KG + DL |
| 33 | cholecystolithiasis | KG + DL |
| 34 | parameningeal embryonal rhabdomyosarcoma | KG + DL |
| 35 | botryoid-type embryonal rhabdomyosarcoma of the vagina | KG + DL |
| 36 | extrahepatic bile duct rhabdomyosarcoma | KG + DL |
| 37 | gout | KG + DL |
| 38 | lipoid nephrosis | KG + DL |
| 39 | gastric linitis plastica | KG + DL |
| 40 | prostate embryonal rhabdomyosarcoma | KG + DL |
| 41 | embryonal extrahepatic bile duct rhabdomyosarcoma | KG + DL |
| 42 | diabetic nephropathy | KG + DL |
| 43 | refractory hematologic cancer | KG + DL |
| 44 | psoriasis | KG + DL |
| 45 | dermatofibrosarcoma protuberans | KG + DL |
| 46 | primary cutaneous T-cell non-Hodgkin lymphoma | KG + DL |
| 47 | liver sarcoma | KG + DL |
| 48 | eye disease | KG + DL |
| 49 | presbyopia | KG + DL |
| 50 | isolated optic neuritis | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.