Mecasermin
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB01277 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 45 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | monosomy X | KG + DL |
| 2 | Wolman disease with hypolipoproteinemia and acanthocytosis | KG + DL |
| 3 | growth hormone insensitivity syndrome with immune dysregulation 2, autosomal dominant | KG + DL |
| 4 | esophageal varices without bleeding | KG + DL |
| 5 | esophageal varices with bleeding | KG + DL |
| 6 | autosomal ichthyosis syndrome with fatal disease course | KG + DL |
| 7 | Gaucher disease | KG + DL |
| 8 | varicose disease | KG + DL |
| 9 | congenital pulmonary lymphangiectasia | KG + DL |
| 10 | cholesteryl ester storage disease | KG + DL |
| 11 | benign neoplasm of adrenal gland | KG + DL |
| 12 | 16q24.1 microdeletion syndrome | KG + DL |
| 13 | primary interstitial lung disease specific to childhood | KG + DL |
| 14 | isolated pulmonary capillaritis | KG + DL |
| 15 | familial apolipoprotein C-II deficiency | KG + DL |
| 16 | Wolman disease | KG + DL |
| 17 | Steel syndrome | KG + DL |
| 18 | reticular dysgenesis | KG + DL |
| 19 | lysosomal acid lipase deficiency | KG + DL |
| 20 | Hurler syndrome | KG + DL |
| 21 | hypophosphatasia | KG + DL |
| 22 | adenosine deaminase deficiency | KG + DL |
| 23 | mitochondrial oxidative phosphorylation disorder due to nuclear DNA anomalies | KG + DL |
| 24 | Scheie syndrome | KG + DL |
| 25 | congenital alveolar capillary dysplasia | KG + DL |
| 26 | mosaic monosomy X | KG + DL |
| 27 | Turner syndrome due to structural X chromosome anomalies | KG + DL |
| 28 | lysosomal storage disease with skeletal involvement | KG + DL |
| 29 | Immunoerythromyeloid hypoplasia | KG + DL |
| 30 | mixed gonadal dysgenesis | KG + DL |
| 31 | severe combined immunodeficiency due to LCK deficiency | KG + DL |
| 32 | Charcot-Marie-Tooth disease | KG + DL |
| 33 | X chromosome number anomaly | KG + DL |
| 34 | sex chromosome disorder of sex development | KG + DL |
| 35 | Cushing disease due to pituitary adenoma | KG + DL |
| 36 | lipase deficiency, combined | KG + DL |
| 37 | hypotrichosis simplex of the scalp | KG + DL |
| 38 | marfanoid hypermobility syndrome | KG + DL |
| 39 | Arts syndrome | KG + DL |
| 40 | severe combined immunodeficiency, autosomal recessive, T cell-negative, B cell-negative, NK cell-positive | KG + DL |
| 41 | Turner syndrome | KG + DL |
| 42 | Fabry disease | KG + DL |
| 43 | lung fibrosis-immunodeficiency-46,XX gonadal dysgenesis syndrome | KG + DL |
| 44 | non-severe combined immunodeficiency | KG + DL |
| 45 | congenital hypotrichosis milia | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.