Prasterone
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB01708 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 73 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | heparin cofactor 2 deficiency | KG + DL |
| 2 | factor 5 excess with spontaneous thrombosis | KG + DL |
| 3 | antithrombin deficiency type 2 | KG + DL |
| 4 | thrombophilia | KG + DL |
| 5 | severe nonproliferative diabetic retinopathy | KG + DL |
| 6 | thrombophilia due to protein S deficiency, autosomal recessive | KG + DL |
| 7 | scleroderma (disease) | KG + DL |
| 8 | complement component 4a deficiency | KG + DL |
| 9 | pseudo-von Willebrand disease | KG + DL |
| 10 | primary release disorder of platelets | KG + DL |
| 11 | acne (disease) | KG + DL |
| 12 | anus disease | KG + DL |
| 13 | granulomatous disease, chronic, autosomal recessive, 5 | KG + DL |
| 14 | inflammatory bowel disease | KG + DL |
| 15 | granulomatous disease with defect in neutrophil chemotaxis | KG + DL |
| 16 | fetal and neonatal alloimmune thrombocytopenia | KG + DL |
| 17 | peeling skin syndrome | KG + DL |
| 18 | spondyloarthropathy, susceptibility to | KG + DL |
| 19 | diabetic retinopathy | KG + DL |
| 20 | seborrheic dermatitis | KG + DL |
| 21 | hereditary North American Indian childhood cirrhosis | KG + DL |
| 22 | functional neutrophil defect | KG + DL |
| 23 | Glanzmann thrombasthenia | KG + DL |
| 24 | autosomal dominant macrothrombocytopenia | KG + DL |
| 25 | limited systemic sclerosis | KG + DL |
| 26 | congenital hypotrichosis with juvenile macular dystrophy | KG + DL |
| 27 | Crohn disease of the esophagus | KG + DL |
| 28 | gout | KG + DL |
| 29 | rheumatoid arthritis | KG + DL |
| 30 | inborn disorder of bilirubin metabolism | KG + DL |
| 31 | benign recurrent intrahepatic cholestasis | KG + DL |
| 32 | ulcerative colitis (disease) | KG + DL |
| 33 | brachydactyly-syndactyly syndrome | KG + DL |
| 34 | C1 inhibitor deficiency | KG + DL |
| 35 | psoriasis | KG + DL |
| 36 | colobomatous microphthalmia-rhizomelic dysplasia syndrome | KG + DL |
| 37 | bilirubin metabolism disease | KG + DL |
| 38 | uterine polyp | KG + DL |
| 39 | systemic sclerosis | KG + DL |
| 40 | epulis | KG + DL |
| 41 | polyp of vocal cord | KG + DL |
| 42 | polyp of middle ear | KG + DL |
| 43 | polyp of ureter | KG + DL |
| 44 | polyp of frontal sinus | KG + DL |
| 45 | polyp of external auditory canal | KG + DL |
| 46 | fibroepithelial polyp | KG + DL |
| 47 | polyp of vulva | KG + DL |
| 48 | neoplastic polyp | KG + DL |
| 49 | familial intrahepatic cholestasis | KG + DL |
| 50 | serpinopathy with toxic serpin polymerization | KG + DL |
(Showing top 50 of 73 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.