Nilotinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB04868 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 46 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | dermatofibrosarcoma protuberans | KG + DL |
| 2 | liposarcoma | KG + DL |
| 3 | ovarian myxoid liposarcoma | KG + DL |
| 4 | Ewing sarcoma | KG + DL |
| 5 | ganglioneuroblastoma (disease) | KG + DL |
| 6 | heart fibrosarcoma | KG + DL |
| 7 | vertebral anomalies and variable endocrine and T-cell dysfunction | KG + DL |
| 8 | kidney fibrosarcoma | KG + DL |
| 9 | fibroblastic neoplasm | KG + DL |
| 10 | conventional fibrosarcoma | KG + DL |
| 11 | low grade fibromyxoid sarcoma | KG + DL |
| 12 | uterine corpus sarcoma | KG + DL |
| 13 | retroperitoneal neoplasm | KG + DL |
| 14 | vulva sarcoma | KG + DL |
| 15 | neuroblastoma | KG + DL |
| 16 | myeloid leukemia | KG + DL |
| 17 | liver fibrosarcoma | KG + DL |
| 18 | fibromatosis, gingival | KG + DL |
| 19 | pregerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma | KG + DL |
| 20 | chronic lymphocytic leukemia/small lymphocytic lymphoma with immunoglobulin heavy chain variable-region gene somatic hypermutation | KG + DL |
| 21 | bone sarcoma | KG + DL |
| 22 | acute lymphoblastic/lymphocytic leukemia | KG + DL |
| 23 | inclusion body myopathy with early-onset Paget disease with or without frontotemporal dementia | KG + DL |
| 24 | hamartoma of lung | KG + DL |
| 25 | fibroma of lung | KG + DL |
| 26 | lung benign neoplasm | KG + DL |
| 27 | junctional epidermolysis bullosa | KG + DL |
| 28 | botryoid-type embryonal rhabdomyosarcoma of the vagina | KG + DL |
| 29 | familial rhabdoid tumor | KG + DL |
| 30 | parameningeal embryonal rhabdomyosarcoma | KG + DL |
| 31 | lung hilum carcinoma | KG + DL |
| 32 | pulmonary sulcus neoplasm | KG + DL |
| 33 | lung germ cell tumor | KG + DL |
| 34 | Leukomelanoderma-infantilism-intellectual disability-hypodontia-hypotrichosis syndrome | KG + DL |
| 35 | extrahepatic bile duct rhabdomyosarcoma | KG + DL |
| 36 | embryonal extrahepatic bile duct rhabdomyosarcoma | KG + DL |
| 37 | Hodgkins lymphoma | KG + DL |
| 38 | prostate embryonal rhabdomyosarcoma | KG + DL |
| 39 | cutaneous leiomyosarcoma (disease) | KG + DL |
| 40 | ovarioleukodystrophy | KG + DL |
| 41 | bone fibrosarcoma | KG + DL |
| 42 | reactive thrombocytosis | KG + DL |
| 43 | liver sarcoma | KG + DL |
| 44 | lung cancer | KG + DL |
| 45 | cutaneous undifferentiated pleomorphic sarcoma | KG + DL |
| 46 | rhabdomyosarcoma (disease) | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.